Journal: Journal of Diabetes Science and Technology

Article Title: Performance Evaluation of a Continuous Glucose Monitoring System under Conditions Similar to Daily Life

doi:

Figure Lengend Snippet: Mean Absolute Relative Difference and Precision Absolute Relative Difference of the Dexcom G4 CGM System (Mean ± Standard Deviation) a

Article Snippet: According to the local distributor, the Dexcom G4 stand-alone system is identical to the Dexcom G4 Platinum system sold in the United States.

Techniques: Standard Deviation

Journal: Journal of Diabetes Science and Technology

Article Title: Performance Evaluation of a Continuous Glucose Monitoring System under Conditions Similar to Daily Life

doi:

Figure Lengend Snippet: Clarke EGA of the paired values obtained with a CGM system (Dexcom G4) and a reference measurement with a BG meter (ACCU-CHEK Aviva). Clinically accurate or acceptable readings are represented by dots in the zones A and B.

Article Snippet: According to the local distributor, the Dexcom G4 stand-alone system is identical to the Dexcom G4 Platinum system sold in the United States.

Techniques:

Journal: Journal of Diabetes Science and Technology

Article Title: Assessing the Accuracy of Continuous Glucose Monitoring (CGM) Calibrated With Capillary Values Using Capillary or Venous Glucose Levels as a Reference

doi: 10.1177/1932296815626724

Figure Lengend Snippet: Mean Absolute Relative Difference (MARD) of Dexcom G4 based on Capillary Versus Venous Glucose References When Calibrating CGM by Capillary Values.

Article Snippet: The purpose of the study was to compare the accuracy of a stand-alone CGM system (Dexcom G4 Platinum, DG4P; Dexcom, San Diego, CA) to that of the Guardian Real-Time CGM system (Enlite, Medtronic, Northridge, CA).

Techniques:

Journal: Journal of Diabetes Science and Technology

Article Title: Assessing the Accuracy of Continuous Glucose Monitoring (CGM) Calibrated With Capillary Values Using Capillary or Venous Glucose Levels as a Reference

doi: 10.1177/1932296815626724

Figure Lengend Snippet: MARD for Dexcom G4 as a continuous function of capillary and venous glucose levels when calibrating CGM with capillary glucose values. Absolute relative difference (ARD) for Dexcom G4 in relation to capillary and venous glucose concentrations is also plotted for all observations in the cohort.

Article Snippet: The purpose of the study was to compare the accuracy of a stand-alone CGM system (Dexcom G4 Platinum, DG4P; Dexcom, San Diego, CA) to that of the Guardian Real-Time CGM system (Enlite, Medtronic, Northridge, CA).

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Summary of Included Studies

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Biomarker Discovery, Control, Injection

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Disease Interventions and Comparators Evaluated in the Primary Economic Model

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Mean A1C Levels, Changes From Baseline With Continuous Glucose Monitoring a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Change in A1C From Baseline and Risk Reduction for Diabetes Complications

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Average Annual Per-Patient Cost of Diabetes Complications and Interventions in Ontario

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Annual Costs of Continuous Glucose Monitoring and Insulin Pump a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Battery

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Costs of Different Diabetes Treatment Technologies a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Cost to Patient of Technologies With Various Levels of Government Funding

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Base Case Analysis

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 1 Results a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 2 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 3 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 4 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 5 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Number of Current Users of Continuous Glucose Monitoring in Ontario by Age Group

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Number of Patients Using Continuous Glucose Monitoring in Ontario, Manufacturer Projections

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Number of Patients Using Continuous Glucose Monitoring in Ontario, Conservative Projections

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Per-Patient Costs of Continuous Glucose Monitoring When Insulin Pump, Insulin, and Supplies Are Publicly Funded

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Per-Patient Costs (All Direct Medical Costs) of Continuous Glucose Monitoring in Ontario

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Per-Patient Costs of Continuous Glucose Monitoring when Insulin Pump, Insulin, and 75% of Sensor Costs Are Publicly Funded

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet:

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Control

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet:

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Control

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Reasons for Including Four Interventions in the Primary Economic Analysis

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a Table A14: Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Summary of Included Studies

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Biomarker Discovery, Control, Injection

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Disease Interventions and Comparators Evaluated in the Primary Economic Model

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Mean A1C Levels, Changes From Baseline With Continuous Glucose Monitoring a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Change in A1C From Baseline and Risk Reduction for Diabetes Complications

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Average Annual Per-Patient Cost of Diabetes Complications and Interventions in Ontario

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Annual Costs of Continuous Glucose Monitoring and Insulin Pump a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Battery

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Costs of Different Diabetes Treatment Technologies a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Cost to Patient of Technologies With Various Levels of Government Funding

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Base Case Analysis

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 1 Results a

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 2 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 3 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 4 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 5 Results

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Number of Current Users of Continuous Glucose Monitoring in Ontario by Age Group

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Number of Patients Using Continuous Glucose Monitoring in Ontario, Manufacturer Projections

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Number of Patients Using Continuous Glucose Monitoring in Ontario, Conservative Projections

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Per-Patient Costs of Continuous Glucose Monitoring When Insulin Pump, Insulin, and Supplies Are Publicly Funded

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Per-Patient Costs (All Direct Medical Costs) of Continuous Glucose Monitoring in Ontario

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Per-Patient Costs of Continuous Glucose Monitoring when Insulin Pump, Insulin, and 75% of Sensor Costs Are Publicly Funded

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet:

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Control

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet:

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques: Control

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Reasons for Including Four Interventions in the Primary Economic Analysis

Article Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a table ft1 table-wrap mode="anchored" t5 Table A14: caption a7 Product Annual Cost Description Standalone CGM Dexcom G4 Platinum Receiver $700 1 unit ($700 per unit) Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $6,420 Dexcom G5 Mobile Transmitters $1,556 4 units ($389 per unit, replaced every 90 days) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total $5,976 Standalone Insulin Pump Insulin pump $1,260 4-year warranty and 1-year extended warranty to meet Assistive Devices Program funding period of 5 years Insulin pump infusion sets $2,494 $20.50 per set every 3 days Insulin pump reservoirs $517 Assumed average use of reservoir: 4.5 days Insulin pump batteries $19 Energizer lithium AA battery Total $4,290 CGM With Insulin Pump Insulin pump (Animas Vibe) $4,290 Transmitters $1,300 2 units ($650 per unit, replaced every 6 months) Sensors $4,420 52 units ($85 per unit, replaced every 7 days) Total: CGM (Dexcom G4 Platinum) $5,720 Total: Insulin pump and CGM $10,140 SAP With LGS Insulin pump (MiniMed Veo) $4,290 Sensors $3,120 52 units ($60 per unit, replaced every 7 days) b Total: CGM $3,120 Total: Insulin pump and CGM $7,410 Open in a separate window Abbreviations: CGM, continuous glucose monitoring; MDI, multiple daily injections; SMBG, self-monitoring of blood glucose; LGS, low glucose suspend; SAP, sensor-augmented pump. a All costs are presented in 2017 Canadian dollars. b According to Medtronic, the average retail price for a CGM sensor is between $50 and $60.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Disease Interventions and Comparators Evaluated in the Primary Economic Model

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Mean A1C Levels, Changes From Baseline With Continuous Glucose Monitoring a

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Change in A1C From Baseline and Risk Reduction for Diabetes Complications

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Average Annual Per-Patient Cost of Diabetes Complications and Interventions in Ontario

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Daily and Annual Costs of Diabetes Treatment Supplies a

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Annual Costs of Continuous Glucose Monitoring and Insulin Pump a

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Cost to Patient of Technologies With Various Levels of Government Funding

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Base Case Analysis

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 1 Results a

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 2 Results

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 3 Results

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 4 Results

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Scenario 5 Results

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Number of Current Users of Continuous Glucose Monitoring in Ontario by Age Group

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Number of Patients Using Continuous Glucose Monitoring in Ontario, Manufacturer Projections

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Ontario Health Technology Assessment Series

Article Title: Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

doi:

Figure Lengend Snippet: Estimated Annual Number of Patients Using Continuous Glucose Monitoring in Ontario, Conservative Projections

Article Snippet: 14 There was no direct evidence that continuous glucose monitoring prevented hospitalizations owing to hypoglycemic events, 25 , 33 , 39 so we did not consider this possibility in our model. table ft1 table-wrap mode="anchored" t5 Table 18: caption a7 Mean Cost ($) a Source First Year Subsequent Years Health State: Diabetes-Related Complications Nephropathy 80 13 O'Brien et al 2003 95 Neuropathy 192 192 O'Brien et al 2003 95 Retinopathy 492 52 O'Brien et al 2003 95 Severe hypoglycemic event (in-patient visit) 3,775 3,775 McQueen et al, 2015 97 Cardiovascular disease 18,682 4,072 O'Reilly et al, 2007 96 Blindness 3,483 2,482 O'Reilly et al, 2007 96 Lower-extremity amputation 43,984 6,024 O'Reilly et al, 2007 96 End-stage renal disease 28,221 12,808 O'Reilly et al, 2007 96 Intervention (Trade Name) Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) 11,811 11,811 Dexcom and Animas b Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) 11,534 11,534 Dexcom and Animas b Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) 9,211 9,211 Medtronic b Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) 10,097 10,097 Dexcom b Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) 8,587 8,587 Dexcom b SMBG plus insulin pump (Animas Vibe or MiniMed Veo) 6,817 6,817 Medtronic and Animas b SMBG plus multiple daily injections 3,677 3,677 Estimate c Open in a separate window Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose. a We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis.

Techniques:

Journal: Journal of Diabetes Science and Technology

Article Title: Performance Evaluation of a Continuous Glucose Monitoring System under Conditions Similar to Daily Life

doi:

Figure Lengend Snippet: Mean Absolute Relative Difference and Precision Absolute Relative Difference of the Dexcom G4 CGM System (Mean ± Standard Deviation) a

Article Snippet: According to the local distributor, the Dexcom G4 stand-alone system is identical to the Dexcom G4 Platinum system sold in the United States.

Techniques: Standard Deviation

Journal: Journal of Diabetes Science and Technology

Article Title: Performance Evaluation of a Continuous Glucose Monitoring System under Conditions Similar to Daily Life

doi:

Figure Lengend Snippet: Clarke EGA of the paired values obtained with a CGM system (Dexcom G4) and a reference measurement with a BG meter (ACCU-CHEK Aviva). Clinically accurate or acceptable readings are represented by dots in the zones A and B.

Article Snippet: According to the local distributor, the Dexcom G4 stand-alone system is identical to the Dexcom G4 Platinum system sold in the United States.

Techniques:

Journal: Journal of Diabetes Science and Technology

Article Title: Assessing the Accuracy of Continuous Glucose Monitoring (CGM) Calibrated With Capillary Values Using Capillary or Venous Glucose Levels as a Reference

doi: 10.1177/1932296815626724

Figure Lengend Snippet: Mean Absolute Relative Difference (MARD) of Dexcom G4 based on Capillary Versus Venous Glucose References When Calibrating CGM by Capillary Values.

Article Snippet: The Dexcom G4 sensor has been shown to be more accurate than the Enlite sensor both in connection to insulin pump and stand-alone systems.

Techniques:

Journal: Journal of Diabetes Science and Technology

Article Title: Assessing the Accuracy of Continuous Glucose Monitoring (CGM) Calibrated With Capillary Values Using Capillary or Venous Glucose Levels as a Reference

doi: 10.1177/1932296815626724

Figure Lengend Snippet: MARD for Dexcom G4 as a continuous function of capillary and venous glucose levels when calibrating CGM with capillary glucose values. Absolute relative difference (ARD) for Dexcom G4 in relation to capillary and venous glucose concentrations is also plotted for all observations in the cohort.

Article Snippet: The Dexcom G4 sensor has been shown to be more accurate than the Enlite sensor both in connection to insulin pump and stand-alone systems.

Techniques:

Journal: Journal of Diabetes Science and Technology

Article Title: Assessing the Accuracy of Continuous Glucose Monitoring (CGM) Calibrated With Capillary Values Using Capillary or Venous Glucose Levels as a Reference

doi: 10.1177/1932296815626724

Figure Lengend Snippet: Mean Absolute Relative Difference (MARD) of Dexcom G4 Based on Capillary Versus Venous Glucose References for Various Rates of Change.

Article Snippet: The Dexcom G4 sensor has been shown to be more accurate than the Enlite sensor both in connection to insulin pump and stand-alone systems.

Techniques:

Journal: Diabetes Spectrum : A Publication of the American Diabetes Association

Article Title: Flash Continuous Glucose Monitoring: Implications for Use of Continuous Data in Daily Diabetes Management

doi: 10.2337/ds18-0059

Figure Lengend Snippet: Features of Selected CGM Systems ( 45 – 47 )

Article Snippet: Dexcom Platinum G4/G5 sensor with G4 Platinum transmitter , Up to 7 days , 2 hours , Every 12 hours , Every 5 minutes , 9% when used with most current Dexcom software , Stand alone with Dexcom G4 receiver and compatible with Animas Vibe and Tandem t:slim insulin pumps.

Techniques: Software

Journal: Journal of Diabetes Science and Technology

Article Title: Performance Evaluation of a Continuous Glucose Monitoring System under Conditions Similar to Daily Life

doi:

Figure Lengend Snippet: Cumulative Percentage of Continuous Glucose Monitoring Readings within 5%, 10%, 20%, and 30% Deviation of Capillary Blood Glucose Readings a

Article Snippet: Continuous Glucose Monitoring Systems In this study, the Dexcom G4 stand-alone CGM system was evaluated; all parts of the system were purchased on the German market.

Techniques:

Journal: Diabetes Spectrum : A Publication of the American Diabetes Association

Article Title: Flash Continuous Glucose Monitoring: Implications for Use of Continuous Data in Daily Diabetes Management

doi: 10.2337/ds18-0059

Figure Lengend Snippet: Features of Selected CGM Systems ( 45 – 47 )

Article Snippet: Dexcom Platinum G4/G5 sensor with G4 Platinum transmitter , Up to 7 days , 2 hours , Every 12 hours , Every 5 minutes , 9% when used with most current Dexcom software , Stand alone with Dexcom G4 receiver and compatible with Animas Vibe and Tandem t:slim insulin pumps.

Techniques: Software